A widely known fact is that the lower genital tract is a haven for a host of bacterial forms that turn pathogenic in nature once the body’s resistance depletes. This categorically leads to undesirable conditions like sterility, fetal loss and untimely labor.

A study was undertaken to examine the advantages of the usage of probiotics like the urogenital probiotic strain, Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 in situations of bad obstetric past while averting post IVF pregnancy complications.

The study sets of seventy pregnant women were administered probiotics strains of GR-1 and RC-14 alongside being given treatment for infertility; and were evaluated against analogous number of seventy cases from a control group that were not administered probiotics but were treated for sterility.

A comprehensive past was taken from all the cases from both sets inclusive of age, numbers of married years, a detailed past of any BOH and any intercession being undertaken in the past.

The study set comprised of ten cases each of chronic leucorrhoea and premature labor, twenty cases of chronic BOH and thirty cases of those that had undergone cervical cerclage.

The control set consisted of sixteen severe leucorrhoea cases, 28 premature labor cases, 24 chronic BOH cases and 2 cervical cerclage cases. All the candidates had wet vaginal preparation and gram staining( Nugent scoring) for bacterial vaginosis that were carried out on 0, 15, 30 and then 60 days. These cases were followed by analytical laparoscopy for tubal patency and pelvic pathology after drawing a vaginal smear swab to examine bacterial flora.

The wet vaginal preparation was then put through gram staining to detect gram positive bacillus. Sterile patients were given an antibiotic course to treat Chlamydia and Mycoplasma. The infertility treatment in both sets differed from 3 months to 5 years. Every fifteen days a wet smear preparation of vaginal flora was done to check the difference subsequent to successful child delivery. There was a steady rise in the number of gram positive bacillus in the study set noted on the days 15, 30 and 60. The vaginal smears taken every fifteen days displayed major variations from anaerobic bacteria to normal vaginal flora with a positive swing in the vaginal pH from alkaline to normal acidic pH.

The conclusion drawn was that probiotics had a major role in treating BOH cases. It additionally averts rising infection, enhances vaginal mucosal immunity and aids in safe delivery.

Popularity: 1% [?]